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1

Intestinal Permeation Enhancers for Oral Peptide Delivery

Maher, Sam, Mrsny, Randall J., Brayden, David J.

Journal:

Advanced Drug Delivery Reviews

Year:

2016

Language:

english

File:

PDF, 1.13 MB

english, 2016

2

Improving the outcomes of biopharmaceutical delivery via the subcutaneous route by understanding the chemical, physical and physiological properties of the subcutaneous injection site

Kinnunen, Hanne M., Mrsny, Randall J.

Journal:

Journal of Controlled Release

Year:

2014

Language:

english

File:

PDF, 849 KB

english, 2014

3

Emerging protein delivery methods

Jeffrey L Cleland, Ann Daugherty, Randall Mrsny

Journal:

Current Opinion in Biotechnology

Year:

2001

Language:

english

File:

PDF, 126 KB

english, 2001

4

Formulation and delivery issues for monoclonal antibody therapeutics

Ann L. Daugherty, Randall J. Mrsny

Journal:

Advanced Drug Delivery Reviews

Year:

2006

Language:

english

File:

PDF, 329 KB

english, 2006

5

Bacterial toxins as tools for mucosal vaccination

Randall J. Mrsny, Ann L. Daugherty, Marian L. McKee, David J. FitzGerald

Journal:

Drug Discovery Today

Year:

2002

Language:

english

File:

PDF, 1.36 MB

english, 2002

6

[ACS Symposium Series] Controlled Drug Delivery Volume 752 (Designing Technologies for the Future) || Controlled Release from Ordered Microstructures Formed by Poloxamer Block Copolymers

Park, Kinam, Mrsny, Randall J.

Year:

2000

Language:

english

File:

PDF, 1.40 MB

english, 2000

7

Emerging technologies that overcome biological barriers for therapeutic protein delivery

Daugherty, Ann L, Mrsny, Randall J

Journal:

Expert Opinion on Biological Therapy

Year:

2003

Language:

english

File:

PDF, 175 KB

english, 2003

8

Taurine maintains and stimulates motility of hamster sperm during capacitation in vitro

Randall J. Mrsny, Lloyd Waxman, Stanley Meizel

Journal:

Journal of Experimental Zoology Part A Ecological Genetics and Physiology

Year:

1979

Language:

english

File:

PDF, 285 KB

english, 1979

9

Evidence suggesting a role for cyclic nucleotides in acrosome reactions of hamster sperm in vitro

Randall J. Mrsny, Stanley Meizel

Journal:

Journal of Experimental Zoology Part A Ecological Genetics and Physiology

Year:

1980

Language:

english

File:

PDF, 473 KB

english, 1980

10

Compaction assay: a rapid and simple in vitro method to assess the responsiveness of a biopolymer matrix to enzymatic modification

Ann L. Daugherty, Thomas W. Patapoff, Ross C. Clark, Dominick V. Sinicropi, Randall J. Mrsny

Journal:

Year:

1995

Language:

english

File:

PDF, 667 KB

english, 1995

11

A Strategy to Identify Stable Membrane-Permeant Peptide Inhibitors of Myosin Light Chain Kinase

Siân-Eleri Owens, W. Vallen Graham, Dario Siccardi, Jerrold R. Turner, Randall J. Mrsny

Journal:

Pharmaceutical Research

Year:

2005

Language:

english

File:

PDF, 305 KB

english, 2005

12

Myosin Light Chain Kinase Inhibition: Correction of Increased Intestinal Epithelial PermeabilityIn Vitro

Linda M. Feighery, Sean W. Cochrane, Teresa Quinn, Alan W. Baird, Daniel O’Toole, Sian-Eleri Owens, Diarmuid O’Donoghue, Randall J. Mrsny, David J. Brayden

Journal:

Pharmaceutical Research

Year:

2008

Language:

english

File:

PDF, 259 KB

english, 2008

13

A simplified procedure for lipid phosphorus analysis shows that digestion rates vary with phospholipid structure

Randall J. Mrsny, Johannes J. Volwerk, O. Hayes Griffith

Journal:

Chemistry and Physics of Lipids

Year:

1986

Language:

english

File:

PDF, 316 KB

english, 1986

14

The second loop of occludin is required for suppression of Raf1-induced tumor growth

Wang, Zili, Mandell, Kenneth J, Parkos, Charles A, Mrsny, Randall J, Nusrat, Asma

Journal:

Year:

2005

Language:

english

File:

PDF, 410 KB

english, 2005

15

Oligopeptide Transporters as Putative Therapeutic Targets for Cancer Cells

Randall J. Mrsny

Journal:

Pharmaceutical Research

Year:

1998

File:

PDF, 303 KB

1998

16

Analysis Methods of Polysorbate 20: A New Method to Assess the Stability of Polysorbate 20 and Established Methods That May Overlook Degraded Polysorbate 20

Mehrnaz Khossravi, Yung-Hsiang Kao, Randall J. Mrsny, Theresa D. Sweeney

Journal:

Pharmaceutical Research

Year:

2002

Language:

english

File:

PDF, 257 KB

english, 2002

17

Percutaneous Absorption of Biologically-Active Interferon-gamma in a Human Skin Graft-Nude Mouse Model

Sarah M. Short, Brian D. Paasch, Jason H. Turner, Norman Weiner, Ann L. Daugherty, Randall J. Mrsny

Journal:

Pharmaceutical Research

Year:

1996

File:

PDF, 13.54 MB

1996

18

An Integrated Method to Determine Epithelial Transport and Bioactivity of Oral Drug Candidatesin Vitro

Werner Rubas, Mary E. M. Cromwell, Randall J. Mrsny, Gladys Ingle, Kathleen A. Elias

Journal:

Pharmaceutical Research

Year:

1996

File:

PDF, 804 KB

1996

19

Transport of Biologically Active Interferon-gamma Across Human Skin in Vitro

Sarah M. Short, Werner Rubas, Brian D. Paasch, Randall J. Mrsny

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 6.34 MB

1995

20

In Vitro Evaluation of Microparticles and Polymer Gels for Use as Nasal Platforms for Protein Delivery

Claudia Witschi, Randall J. Mrsny

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 2.28 MB

1999

21

Book Reviews

Randall J. Mrsny

Journal:

Pharmaceutical Research

Year:

2004

Language:

english

File:

PDF, 91 KB

english, 2004

22

[ACS Symposium Series] Controlled Drug Delivery Volume 752 (Designing Technologies for the Future) ||

Park, Kinam, Mrsny, Randall J.

Year:

2000

Language:

english

File:

PDF, 1.55 MB

english, 2000

23

Procedures for obtaining high percentages of viable in vitro capacitated hamster sperm

Chung W. Lui, Randall J. Mrsny, Stanley Meizel

Journal:

Molecular Reproduction and Development

Year:

1979

Language:

english

File:

PDF, 286 KB

english, 1979

24

[ACS Symposium Series] Controlled Drug Delivery Volume 752 (Designing Technologies for the Future) || Self-Emulsifying Drug Delivery Formulations in the 21 st Century: Challenges and Opportunities

Park, Kinam, Mrsny, Randall J.

Year:

2000

Language:

english

File:

PDF, 1.70 MB

english, 2000

25

The colon as a site for drug delivery

Randall J. Mrsny

Journal:

Journal of Controlled Release

Year:

1992

Language:

english

File:

PDF, 1.38 MB

english, 1992

26

Regulation of intestinal epithelial function: a link between opportunities for macromolecular drug delivery and inflammatory bowel disease

Dario Siccardi, Jerrold R. Turner, Randall J. Mrsny

Journal:

Advanced Drug Delivery Reviews

Year:

2005

Language:

english

File:

PDF, 385 KB

english, 2005

27

Adhesion proteins in cellular tight junctions: critical components in the modulation of paracellular permeability

Randall J. Mrsny, Asma Nusrat

Journal:

Advanced Drug Delivery Reviews

Year:

2005

Language:

english

File:

PDF, 51 KB

english, 2005

28

Lessons from nature: “Pathogen-Mimetic” systems for mucosal Nano-medicines

Randall J. Mrsny

Journal:

Advanced Drug Delivery Reviews

Year:

2009

Language:

english

File:

PDF, 626 KB

english, 2009

29

Seventh International Nanomedicine and Drug Delivery Symposium (NanoDDS'09)

Ralph Lipp, Randall Mrsny, Kinam Park

Journal:

Journal of Controlled Release

Year:

2010

Language:

english

File:

PDF, 106 KB

english, 2010

30

Oral drug delivery research in Europe

Randall J. Mrsny

Journal:

Journal of Controlled Release

Year:

2012

Language:

english

File:

PDF, 200 KB

english, 2012

31

Epithelial application of Pseudomonas aeruginosa exotoxin A results in a selective targeting to cells in the liver, spleen and lymph node

Ann L Daugherty, Marian L McKee, David J FitzGerald, Randall J Mrsny

Journal:

Journal of Controlled Release

Year:

2000

Language:

english

File:

PDF, 1.13 MB

english, 2000

32

Modulation of tight junction function by G protein-coupled events

Ann M Hopkins, Dinxi Li, Randall J Mrsny, Shaun V Walsh, Asma Nusrat

Journal:

Advanced Drug Delivery Reviews

Year:

2000

Language:

english

File:

PDF, 161 KB

english, 2000

33

Transcellular uptake mechanisms of the intestinal epithelial barrier Part one

Ann L. Daugherty, Randall J. Mrsny

Journal:

Pharmaceutical Science & Technology Today

Year:

1999

Language:

english

File:

PDF, 224 KB

english, 1999

34

Regulation of the intestinal epithelial paracellular barrier

Ann L Daugherty, Randall J Mrsny

Journal:

Pharmaceutical Science & Technology Today

Year:

1999

Language:

english

File:

PDF, 558 KB

english, 1999

35

[ACS Symposium Series] Controlled Drug Delivery Volume 752 (Designing Technologies for the Future) || Controlled Drug Delivery: Present and Future

Park, Kinam, Mrsny, Randall J.

Year:

2000

Language:

english

File:

PDF, 1.55 MB

english, 2000

36

Appearance of Additional Ouabain Binding Sites on Platelet Surfaces Following Activation

Tracie Bork, Randall J. Mrsny

Journal:

Experimental Cell Research

Year:

1993

File:

PDF, 899 KB

1993

37

Initial evidence for the modification of hamster sperm Na+, K+-ATPase activity by cyclic nucleotide-mediated processes

Randall J. Mrsny, Stanley Meizel

Journal:

Biochemical and Biophysical Research Communications

Year:

1983

Language:

english

File:

PDF, 1.12 MB

english, 1983

38

New insights into mechanisms of gastrointestinal inflammation and cancer

Stephen G Ward, Randall Mrsny

Journal:

Current Opinion in Pharmacology

Year:

2009

Language:

english

File:

PDF, 95 KB

english, 2009

39

Sustained release formulations of rhVEGF165 produce a durable response in a murine model of peripheral angiogenesis

Ann L. Daugherty, Linda K. Rangell, Renee Eckert, Jose Zavala-Solorio, Frank Peale, Randall J. Mrsny

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2011

Language:

english

File:

PDF, 2.05 MB

english, 2011

40

Mucosal administration of a chimera composed of Pseudomonas exotoxin and the gp120 V3 loop sequence of HIV-1 induces both salivary and serum antibody responses

Randall J Mrsny, Ann L Daugherty, Charlotte M Fryling, David J FitzGerald

Journal:

Year:

1999

Language:

english

File:

PDF, 267 KB

english, 1999

41

Pharmacological modulation of the tissue response to implanted polylactic-co-glycolic acid microspheres

Ann L. Daugherty, Jeffrey L. Cleland, Eileen M. Duenas, Randall J. Mrsny

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

1997

Language:

english

File:

PDF, 1.89 MB

english, 1997

42

A Key Claudin Extracellular Loop Domain is Critical for Epithelial Barrier Integrity

Randall J. Mrsny, G. Thomas Brown, Kirsten Gerner-Smidt, Andre G. Buret, Jon B. Meddings, Clifford Quan, Michael Koval, Asma Nusrat

Journal:

The American Journal of Pathology

Year:

2008

Language:

english

File:

PDF, 1.47 MB

english, 2008

43

[ACS Symposium Series] Controlled Drug Delivery Volume 752 (Designing Technologies for the Future) || A Novel Composite Membrane for Temperature- and pH-Responsive Permeation

Park, Kinam, Mrsny, Randall J.

Year:

2000

Language:

english

File:

PDF, 1.20 MB

english, 2000

44

Inhibition of hamster sperm Na+, K+-ATPase activity by taurine and hypotaurine

Randall J. Mrsny, Stanley Meizel

Journal:

Year:

1985

Language:

english

File:

PDF, 264 KB

english, 1985

45

Oral peptide delivery: prioritizing the leading technologies

Brayden, David J, Mrsny, Randall J

Journal:

Therapeutic Delivery

Year:

2011

Language:

english

File:

PDF, 1.02 MB

english, 2011

46

A strategy to improve selectivity and targeting to epithelial-derived cancer cells

Liu, Keyi, Hearne, Kenneth, Mrsny, Adrienne, Staka, Cindy, Mrsny, Randall J.

Journal:

Journal of Controlled Release

Year:

2012

Language:

english

File:

PDF, 551 KB

english, 2012

47

Real-time imaging of occludin and actin in live cells reveals early events associated with loss of tight junction barrier properties

Le Shen, Randall J. Mrsny, Jerrold R. Turner

Journal:

Gastroenterology

Year:

2003

Language:

english

File:

PDF, 186 KB

english, 2003

48

Pharmacological modulation of transepithelial resistance by a membrane permeant oligopeptide myosin light chain kinase inhibitor

Yevgeny Zolotarevsky, Randall J. Mrsny, Jerrold R. Turner

Journal:

Gastroenterology

Year:

2001

Language:

english

File:

PDF, 194 KB

english, 2001

49

A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease

Yevgeny Zolotarevsky, Gail Hecht, Athanasia Koutsouris, Deborah E. Gonzalez, Cliff Quan, Jeffrey Tom, Randall J. Mrsny, Jerrold R. Turner

Journal:

Gastroenterology

Year:

2002

Language:

english

File:

PDF, 480 KB

english, 2002

50

Distinct temporal-spatial roles for rho kinase and myosin light chain kinase in epithelial purse-string wound closure

John M. Russo, Peter Florian, Le Shen, W. Vallen Graham, Maria S. Tretiakova, Alfred H. Gitter, Randall J. Mrsny, Jerrold R. Turner

Journal:

Gastroenterology

Year:

2005

Language:

english

File:

PDF, 1.70 MB

english, 2005

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